The Blessed Sacrament Chapel is located behind the Sanctuary, at the east end of the Cathedral. Here, in the tabernacle, the Blessed Sacrament (the Eucharist, Communion) is kept. From the tabernacle communion is taken to those who are sick or dying. This chapel is a special place of prayer, since the Eucharist is the real presence of Christ. On the altar beneath the tabernacle there is a fine carving of the Last Supper.
The sides of the chapel are decorated with wall paintings, possibly by Henry Doyle. Beneath, choir stalls with carved misericords bear the coats of arms of the first four bishops of Lancaster.
Behind the altar and triptych, a number of saints are depicted. They are painted on linoleum, a material which was Lancaster's main manufacturing product for many years. These paintings are in need of restoration, which could prove to be a difficult task, as paintings on linoleum are extremely rare.